February 25, 2009
Can psoriasis be inherited from parents?
The genetics of psoriasis is currently the subject of active medical research. Not much is known about gene(s) that may be involved in causing psoriasis.
This is complicated by the fact that there are various forms of psoriasis associated with different complications and response to the same medication.
It is known that there is a higher frequency of psoriasis amongst relatives of individuals with this condition. Which of the relatives get the disease cannot be predicted, at the present time.
There appears to be several genes that result in this condition. As well, specific environmental factors are required to express this disease. Thus there are many factors that need to be present, in order to get the skin plaques associated with this disease.
Genetic studies have focused on genes on chromosome 1, 2, 6, 8, 16, 17, 19 and 20. At these locations there appears to be genes associated with psoriasis. From these studies it appears that the PSORS1 gene on chromosome 6 is the most common gene associated with psoriasis.
Intense molecular studies are now focused on the PSORS1 region of chromosome 6 to determine the exact nature of some of the most common genes associated with psoriasis
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